3M School of Purification
The Future of Chromatography
Master Class Webinar Recordings
Chromatography is a universal technique within the downstream processing of biopharmaceuticals. Its versatility is linked to the ability to separate species based on various properties such as charge, hydrophobicity or specific interactions (e.g. between antibody and antigen) based on the ligand used. But that is only half the story, the matrix on which the ligand is immobilised also plays an important role.
Delve into the world of chromatography with our Master Class webinar recordings, designed to encompass the topics most impacting chromatography in bioprocessing.
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Bioprocessing Chromatography 101
In the first module, we cover:- The basics of chromatography
- Challenges and limitations of existing chromatography media
- What does the future of chromatography look like?
- Next-generation downstream chromatography technologies
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Bioprocessing Method Development
In the second module, we cover:- The basics of conducting a trial, including the importance of design of experiment and key factors to note when looking at data trends.
- Two example case studies focused on developing experience in real-world application.
- Factors influencing chromatographic performance.
- Next-generation downstream chromatography technologies
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Problematic HCP in Bioprocessing
In the third module, we cover:- The basics of bioprocess simplification and intensification
- Process strategy vs process reality
- Typical issues with problematic HCP and its real-world solutions
- Next-generation downstream chromatography technologies
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Viral Clearance in Bioprocessing
In the fourth module, we cover:- A comprehensive overview of viral clearance and its best practices
- Comparison between membrane chromatography and traditional AEX columns
- A walk-through of real-world scenarios dealing with viral clearance
- Next-generation downstream chromatography technologies
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Next Generation Purification Processes in Bioprocessing
In the fifth module, we cover:- A real-world case study summarising and expanding upon content from the previous four modules
- How to leverage new technologies to deliver the best service and performance to collaborators
- What does the future of chromatography look like?
- Next-generation downstream chromatography technologies
Speaker Biography
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Jennifer Heitkamp, M.S.
Advanced Application Development Specialist, 3M's Separation and Purification Sciences Division
With 40 years of experience, Jennifer is an expert in chromatographic methods for quantification, size exclusion, ion exchange (including viral clearance), and hydrophobic interactions. As a key member in product development, she is instrumental in contributing to the launch of multiple 3M products, including 3M Polisher ST and many others.
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Joris Van de Velde, M.S.
Bioprocess Applications Specialist, 3M's Separation and Purification Sciences Division
Joris holds a Masters of Science of Chemical Engineering from KU Leuven University and a postgraduate degree in Marketing Management from EHSAL Management School in Belgium. At 3M, his responsibilities are focused in producing and evaluating innovative purification technologies and biopharmaceutical manufacturing companies. He has supported customers all over the world, including Belgium, Netherlands, the United States, and multiple regions, and currently resides in Boston.
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Jonathan Hester, Ph.D.
Division Scientist, 3M's Separation and Purification Sciences Division
Jonathan holds a Bachelor's of Science in Materials Science and Engineering from Purdue University and a Ph.D. in Polymer Science from M.I.T. Since 2000, he has had multiple technical roles at 3M, ranging from technology development at 3M’s Corporate Research Laboratory to most recently, product development in the Separation & Purification Sciences Division, where he works on the development of liquid separation solutions for biopharmaceutical processing. He is a co-inventor on 22 patent publications related to liquid separation materials, devices, and processes.
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Matt Peters
Biopharmaceutical Applications Specialist, 3M's Separation and Purification Sciences Division
Matt received his B.S. in Chemistry from the University of Connecticut in 2003, and brings 19+ years of experience in filtration and separation along with an extensive background in analytical testing to his application support work. He gained a deep knowledge of 3M’s depth filtration and membrane filtration products as he developed and performed test methods. Matt then worked as a Senior Product Development Chemist for 3M with emphasis on development of biopharmaceutical purification products. Most recently Matt was an Application Development Specialist responsible for developing the application launch data package for 3M™ Polisher ST.
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David Chau, Ph.D.
Global Bioprocess Application Specialist, 3M's Separation and Purification Sciences Division
David has over 15 years of research experience in the biotechnology industry where he earned his Ph.D at the University of Minnesota in Twin Cities. He is responsible for developing data packages and new product application for novel downstream technology. He also helps to support and drive collaborations with key industry leaders around the globe.
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