Webinar 2: Improving downstream process efficiency with novel ligand chemistries 


  • Summary  

    Date: Wednesday April 17, 2024
    Time: 11 am CET / 10 am GMT
    Speakers: Dr. Sophie Muczenski and Dr. Sean Anderson
    Event language: English 

    The School of Purification continues with “Improving downstream process efficiency with novel ligand chemistries."

    Intensification and simplification of the downstream biopharmaceutical process enables higher productivity, decreased product mass intensity, and increased sustainability.

    In this seminar we will specifically cover:

    How novel ligands and improved upstream processes bring value to the entire process with a focus on intensified downstream polishing operations. 

    A case study collaboration between Gilead and 3M - How Gilead was able to replace their post-viral inactivation depth filter and flow through AEX column with a novel fiber chromatography device, resulting in process simplification, yield increase, and a decrease in PMI.  


    Meet the presenters:

    Sophie Muczenski, Ph.D.

    Sophie Muczenski, Ph.D. is an Application Engineering Specialist focusing on filtration in biopharmaceutical applications. She is located in Germany and supporting customers in the Central Europe Region. The focus of her work is on replicating existing applications as well as developing new applications and deploying new technologies at biopharmaceutical manufacturers. Before joining 3M  Sophie graduated at the University of Hohenheim in Stuttgart following her study of Biochemistry at the Martin-Luther-University Halle/Saale.  

    Sean Anderson, Ph.D.

    Sean Anderson, Ph.D. is a Bioprocess Application Specialist in 3M’s Separation and Purification Sciences Division. With over ten years of experience in the biotechnology industry, he has worked in many aspects of the biopharma business including R&D, product development, process development, analytical development and manufacturing, quality, and business development. Currently, he is responsible for product application and driving collaborations with key industry leaders around the globe, with a focus in the Southern California region.


    3M School of Purification 

    The 3M School of Purification is a program designed by a team of 3M Technical Experts, with the purpose of educating the industry on a range of important biopharmaceutical separation and purification topics through a series of interactive and engaging webinars. To learn more about 3M School of Purification and to view all previous webinars On-Demand, visit our website:  School of Purification (3m.com) 

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